What is GcMAF?

GcMAF is a substance that activates the body’s immune system, naturally.

What does GcMAF stand for?

GcMAF stands for Gc protein derived macrophage activating factor. This is a protein that is formed by modifying the Vitamin D binding protein, which occurs when enzymes are released by B-cells and T-cells. Once GcMAF is released, it in turn activates macrophages, which are hardy white blood cells that play an important role in managing our immunity and well as putting up defenses within the body. 

So what is MAF supposed to be? MAF stands for macrophage activating factor. As outlined above, the GcMAF protein acts as a macrophage activating factor, helping you build up your immunity and thus protecting you against a number of diseases and disorders.

A strong immune system does more than you realize

Now that we know what GcMAF and MAF are, we need to look a little bit closer at the body’s immune responses, and how they work. 

The more we research immunity, the more we understand its impact on health. Poor immunity goes beyond the ability to resist infections, it also increases the likelihood of poor outcomes for chronic diseases, autoimmune conditions, inflammation and neurological disorders. For the body to stay at homeostasis, or the ideal state in which all systems are balanced and functioning optimally, the organs and central nervous system need to be effectively communicating with the immune system. A weak immune system is unable to regulate these systems, which means the body has no defense mechanism against disorders and diseases. 

It is not just the body that is impacted, the body’s neurological systems are affected by weakened immunity. As per research,  autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are the result of immune dysregulation, inflammation and microglia dysfunction negatively impacting neural circuits.  

Immune dysregulation is when a body generates an immune response against its own cells, molecules or tissues, usually because of an unimportant foreign particle that normal immune systems would not ignore. Naturally, this results in distress. Dysregulation is a feature of autoimmune and immunodeficiency conditions.

How MAF supplements work through the microglia

Microglia, which are macrophages, are highly specialized immune cells present in the central nervous system. They keep the brain healthy by repairing cells, controlling inflammation and combating foreign substances. They play a key role in managing and maintaining brain functions. 

As microglia are macrophages, the GcMAF’s activating mechanism impacts these immune cells, which in turn is beneficial for anyone suffering from autism, ADHD, Alzheimer's, dementia, headaches, migraines, depression, and multiple sclerosis. Once activated, the microglia can normalize and regulate immunological conditions associated with these disorders through several mechanisms:

1. Phagocytosis: Microglia clears cellular debris, pathogens, and damaged cells, thereby halting brain inflammation caused by pathogens.
2. Cytokine production: Microglia release cytokines, signaling molecules that modulate the immune response. They can produce anti-inflammatory cytokines, which stop inflammation and promote tissue repair in the brain.
3. Modulation of other immune cells: Microglia interacts with other immune cells such as T cells and macrophages, influencing the overall immune response in the brain.
4. Neuroprotection: Microglia release proteins that support the survival of neurons and other brain cells, providing protection against damage and its progression.
5. Neurotrophic factor release: Activated microglia release neurotrophic factors that support the growth and survival of neurons. These factors promote the proliferation of neural progenitor cells and enhance the survival of newly generated neurons, which is crucial for individuals with weak neuron connectivity in conditions like autism and ADHD.
6. Removal of inhibitory molecules and debris: Microglia clears inhibitory molecules and debris from the environment surrounding injured neurons, creating a more favorable environment for neuronal growth and regeneration.
7. Interaction with brain cells: Microglia interacts with astrocytes and other cells in the brain to coordinate neurodegenerative processes and facilitate the formation of new neural connections.
8. Regulation of behavior and movement: Dysfunction of microglia in the brain is believed to contribute to symptoms observed in autism and ADHD, highlighting their role in regulating behavior and movement.

Empower your body with MAF supplements

Our dietary MAF products empower your body to aid in its natural healing processes. Derived from bovine colostrum, it is patented and approved for use around the world. 

Sufferers of chronic fatigue will find that they get relief within three days or so, while diseases and development disorders start showing improvements anywhere from 2 weeks to a month.

What conditions can you treat with MAF?

As discussed, dietary MAF supplements are highly effective in immune disorders or diseases where a strong immunity is key. This can range from simple viral infections to more serious ailments like:

• Parkinson’s disease 
• Insomnia
• Rheumatoid arthritis 
• Multiple sclerosis
• Urinary tract infection (UTI)
• Polycystic ovary syndrome (PCOS)
• Leaky gut syndrome
• Tuberculosis 
  

Take a look at this full list of diseases treated by GcMAF for more details. 

Conventional medicine relies on medications to manage symptoms, resulting in long-term side effects. On the other hand, MAF supplements work to address the root causes of these conditions, effectively treating and preventing their recurrence without causing harm. 

For example, in Alzheimer's and Parkinson's diseases, the overproduction of TNF-alpha disrupts synaptic communication in the brain. MAF activates macrophages to counteract TNF-alpha by occupying its receptors and improving blood flow in the brain.

How to check if MAF treatment is working

There are two ways you can check if your treatment is working:

• Regular blood tests: Look for improvements in your monocyte count
• Nagalase testing: Viruses, diseases, cancerous cells and conditions like autism produce elevated nagalase, which should start to decrease after continuous GcMAF treatment. Test before and after to understand how you are progressing.